Bioness NESS L300 Plus Manuel d'utilisateur

The L300® Plus System

L300 Large Electrodes Copyright 2011 Bioness Inc.

Copyright 2011 Bioness Inc. L300 Plus System

Challenges of Neurologic Gait  Usually Involves Several Joints/Muscle Groups  Complicated by Impairment in Timing, Control, and Sensation  Difficu

Challenges of Neurologic Gait  Solutions often fall short and compensatory in nature  No “one” solution works for everyone  Proximal control diffic

Without Stimulation With Stimulation L300 Plus System: Design Concept Example Stimulation of Hamstrings During Stance

Copyright 2011 Bioness Inc. L300 Plus System: Select Design Achievements  Addresses Dysfunction of Hamstrings and Quadriceps and Associated Gait/Func

Copyright 2011 Bioness Inc. L300 Plus System: Potential Impact on Gait  Better Knee Control  Increased Step Length  Increased Stance Time  Better

L300 Plus System Components Copyright 2011 Bioness Inc.  New components include the Thigh Cuff with Stimulator and multi-function Control Unit  Use

© 2011 Bioness Inc. Confidential. 18 Thigh Functional Stimulation Cuff  Elongation bar and adjustable straps for length and girth tuning  12 “Quick

 Position on Thigh for Quads versus Hamstrings  Anatomical landmarks ensure accurate electrode placement  Comfortable “closed” cell materials allow

Objectives  Introduction to Bioness  Introduce Large Electrodes, L300 Systems  Introduce the L300 Plus System – Background – Features – Value – Pil

L300 Plus Control Unit Copyright 2011 Bioness Inc. Control Unit

L300 Plus Control Unit Copyright 2011 Bioness Inc. Control Unit

L300 Plus Clinic Value Copyright 2011 Bioness Inc.

Intelli-Gait Plus Software Copyright 2011 Bioness Inc. Software

Intelli-Gait Plus Software Copyright 2011 Bioness Inc. Software

© 2011 Bioness Inc. Confidential. 25 L300 Plus Videos  Provides Immediate Orthotic Benefit  Addresses issues in Swing and Stance  Therapeutic Impac

L300 Plus Videos Copyright 2011 Bioness Inc. No Stimulation L300 Plus

L300 Plus Feasibility Study © 2011 Bioness Inc. Confidential. 27 Subjects:  Forty-five (45) subjects suffering from foot drop and thigh muscles weakn

L300 Plus Feasibility Study © 2011 Bioness Inc. Confidential. 28  The study protocol duration for each subject was six weeks.  Case Series Trial

L300 Plus Feasibility Study: Gait Speed © 2011 Bioness Inc. Confidential. 29 0,2 0,3 0,4 0,5 0,6 0,7 Baseline 6 Weeks M/S L300 Plus Orth

Pacesetter Systems, Inc. © 2011 Bioness Inc. Confidential.

L300 Plus Feasibility Study: Gait Speed © 2011 Bioness Inc. Confidential. 30 0,2 0,3 0,4 0,5 0,6 Baseline 6 Weeks M/S L300 Plus

L300 Plus Feasibility Study: Symmetry © 2011 Bioness Inc. Confidential. 31 0 0,1 0,2 0,3 0,4 0,5 0,6 0,7 No Stim Baseline L300 Plus Baseline L300 Plus

L300 Plus Feasibility Study: Outcome © 2011 Bioness Inc. Confidential. 32 Knee Hyperextension exacerbated with speed

L300 Plus Feasibility Study: Outcome © 2011 Bioness Inc. Confidential. 33 L300 Plus at Comfortable Pace: HS in Stance/Preswing

L300 Plus Feasibility Study: Fast Pace © 2011 Bioness Inc. Confidential. 34 Fast Pace No Stimulation

L300 Plus Feasibility Study: Fast Pace © 2011 Bioness Inc. Confidential. 35 L300 Plus at Fast Pace: HS in Stance/Pre-swing

Feasibility Study Summary  Clinical need for knee control following UMN disorder is evident  Current technology is limited, mainly compensatory, and

© 2011 Bioness Inc. Confidential. 37 L300 Plus Features Review  Wireless Communication  Operates off the same Clinician’s Programmer as the L300  R

technology 2004 - 2010 H200® EXOSKELETAL IMPLANTABLES L300 ® Microstimulators Bioness Neuromodulation Technology L300 Plus™ H200 ® Wireless Copyright

technology Bioness Rehabilitation Technology Complete Gait Systems Copyright 2011 Bioness Inc.

© 2011 Bioness Inc. Confidential. 6 Gait Dysfunction and Rehabilitation Connections with Ambulation Status:  Disability  Discharge  Falls Risk  We

© 2011 Bioness Inc. Confidential. 7 FES Support and Development  Recommend treatment with FES for stroke patients with impaired muscle contraction.

The Large Cloth Electrode, L300 Systems

Simplify the Fitting Process  Large Size Cloth-Based Electrode  Simplifies fitting, greatly reduces set-up (no fitting cables)  Improves Recruitmen